A. IgA nephropathy – Explanation
IgA nephropathy (Berger’s disease)
Features
- Young male, recurrent episodes of macroscopic haematuria
- Typically usually with an upper respiratory tract infection or, less often,
gastroenteritis. Most patients have a history of an upper respiratory tract infection
and, either at the onset or within the first 24-48 hours, there is gross haematuria that
lasts for less than three days. The urine is red or brown and there may also be loin
pain. - Alternatively, there may be no symptoms but urine shows erythrocytes, casts and
proteinuria. - It is associated with a number of other diseases, including Henoch-Schönlein
purpura. - Of those that do not remit, there is a slow progression to ESKD.
Differentiating between IgA nephropathy and post-streptococcal
IgA nephropathy | Post-streptococcal glomerulonephritis |
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