Although type 3 von Willebrand disease is actually autosomal recessive, majority of von Willebrand’s disease is autosomal dominant. Von Willebrand disease The 3 important points you need to know in Von Willebrand disease in PLAB is: 1. It presents with …
The evidence of increased MCHC, gallstones and family history points towards hereditary spherocytosis. Hereditary Spherocytosis Hereditary Spherocytosis is the most common inherited RBC membrane defect characterized by variable degrees of haemolysis, spherocytic RBCs with increased osmotic fragility. Approximately 75% of …
Polycystic ovary syndrome (PCOS) would fit the best among the answers. Cushing’s would be a consideration here as it can sometimes cause amenorrhoea too. FSH LH OESTRADIOL PROLACTIN TABLE  FSH LH Oestradiol Prolactin Polycystic ovarian syndrome(PCOS) Normal Increased Note: …
This is a very straightforward question but it does test your knowledge of lung function testing thoroughly. The pulmonary indices indicate a restrictive lung disease. The only choice that is a restrictive lung disease is pulmonary fibrosis. Asthma, bronchiectasis, pulmonary …
The chest X-ray clearly shows a right pneumothorax with right lung collapse and mediastinal shift to the left. The right lung is completely compressed and the trachea is pushed to the left. It is obvious that there are no lung …
This woman has become acutely breathless from a pulmonary emboli. She is hypoxic and, as a reflex to this, is hyperventilating (as evidenced by the low PaCO2). As a result, she has developed an alkalosis. The other options are much …
The answer here is to increase the dose of ICS. The patient is considered to be at step 4 of the BTS guideline which recommends increasing the ICS dose to 800 mcg/day or to consider a trial of Theophylline. Be …
Prolonged plane journey is a recognized risk factor for thromboembolism and hencepulmonary embolism as well. Sharp chest pain and breathlessness after 3 days of planejourney is highly suggestive of pulmonary embolism. CTPA is the answer here as it is thebest …
The features described is diagnostic of left sided tension pneumothorax Tension Pneumothorax Presentation – Acute respiratory distress – Hypotension – Raised jugular venous pressure – Tracheal deviation away from the pneumothorax side – Reduced air entry on affected side Management …
The patient is at risk of acquiring a blood-borne viral infection such as hepatitis B, hepatitis C and HIV. The biter is known to be a drug addict, and therefore is at a higher risk of being infected with a …