C. Labetalol – Explanation
Labetalol is the most studied antihypertensive in pregnancy with the safest profile.
Pregnancy Induced Hypertension
Te gehneral management for gestational hypertension can be summarized below:
| Degree of Hypertension | Mild Hypertension (140/90 to 149/99 mmHg) |
Moderate Hypertension (150/100 to 159/109 mmHg) |
Severe Hypertension (160/110 mmHg or higher) |
| Admit to Hospital | No | No | Yes |
| Treat | No | With oral labetalol as first-line treatment to keep:
|
With oral labetalol as first-line treatment to keep:
|
Alternatives that are commonly used in pregnancy are methyldopa and nifedipine
| Labetalol | 100 mg bd up to 600 mg qds | Avoid in asthma | OK |
| Methyldopa | 250 mg bd up to 1 g tds | OK | |
| Nifedipine | 10 mg bd up to 30 mg tds | OK |
